Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17458125 | 0.85 | PIK3CD (0.64) | PIK3CDPIK3R1 | |
| SCHEMBL17458123 | 0.85 | PIK3CD (0.64) | PIK3CDPIK3R1 | |
| SCHEMBL23912244 | 0.80 | PIK3CD (0.57) | PIK3CDSMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL23912255 | 0.78 | PIK3CD (0.54) | PIK3CDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL17458013 | 0.78 | PIK3CD (0.61) | PIK3CDPIK3R1 | |
| SCHEMBL17458017 | 0.78 | PIK3CD (0.61) | PIK3CDPIK3R1 | |
| SCHEMBL17235505 | 0.75 | ESR1 (0.60) | SMN1; SMN2ALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL20404396 | 0.75 | PIK3CD (0.57) | PIK3CDSMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL23912309 | 0.75 | HRH3 (0.60) | PIK3CDALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL23912241 | 0.75 | HRH3 (0.60) | PIK3CDALDH1A1MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |