Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.54 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810876 | 1.00 | HRH3 (0.66) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL26722832 | 0.96 | HRH3 (0.59) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL10953965 | 0.85 | HRH3 (0.88) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL9264606 | 0.84 | HRH3 (0.48) | HRH3POLBHDAC1ALDH1A1MEN1 | |
| SCHEMBL15921223 | 0.83 | HRH3 (0.66) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL15921069 | 0.81 | HRH3 (0.62) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL22084115 | 0.78 | S1PR4 (0.45) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL8809884 | 0.77 | HRH3 (0.68) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL11615671 | 0.77 | POLB (0.93) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL21799935 | 0.77 | HRH3 (0.72) | HRH3POLBHDAC1CXCR4CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892278-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-10-13 | — | — | EP | disclosed |