Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 3/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847296 | 0.93 | HRH3 (0.71) | HRH3MEN1KMT2ARAB9AGRIN2B | |
| SCHEMBL10789534 | 0.93 | HRH3 (0.71) | HRH3MEN1KMT2ARAB9AGRIN2B | |
| SCHEMBL294763 | 0.93 | HRH3 (0.71) | HRH3MEN1KMT2ARAB9AGRIN2B | |
| SCHEMBL24574127 | 0.93 | HRH3 (0.71) | HRH3MEN1KMT2ARAB9AGRIN2B | |
| Hydrochloric Acid SCHEMBL11782513 | 0.91 | HRH3 (0.69) | HRH3MEN1KMT2ARAB9AGRIN2B | |
| Hydrochloric Acid SCHEMBL11781778 | 0.91 | HRH3 (0.69) | HRH3MEN1KMT2ARAB9AGRIN2B | |
| SCHEMBL2954218 | 0.91 | GRIN2B (0.69) | HRH3MEN1KMT2ARAB9AGRIN2B | |
| SCHEMBL433970 | 0.91 | GRIN2B (0.69) | HRH3MEN1KMT2ARAB9AGRIN2B | |
| SCHEMBL4173336 | 0.91 | GRIN2B (0.69) | HRH3MEN1KMT2ARAB9AGRIN2B | |
| Bromide SCHEMBL18131548 | 0.89 | HRH3 (0.67) | HRH3MEN1KMT2ARAB9AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |