Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28931246 | 0.84 | CA1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22084633 | 0.83 | ALOX5 (0.47) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22084059 | 0.83 | ALOX5 (0.47) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL23912329 | 0.80 | DRD2 (0.48) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22084631 | 0.78 | ALOX5 (0.47) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL23912288 | 0.71 | DRD2 (0.51) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL21553452 | 0.70 | ALDH1A1 (0.57) | CA12CA1CA2CA3CA4 | |
| SCHEMBL28667747 | 0.70 | MEN1 (0.49) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL14673010 | 0.69 | KDM1A (0.64) | MAOAMAOBALOX5ALDH1A1DRD2 | |
| SCHEMBL1242008 | 0.69 | ALOX5 (0.56) | MMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892278-B1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2024-02-28 | — | — | EP | disclosed |
| EP-3892278-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-10-13 | — | — | EP | disclosed |