SCHEMBL23912468

SCHEMBL23912468

CC1=CCN=C(NC(=O)NC(CCCCNC(=O)Nc2nc(=O)cc(C)[nH]2)C(=O)O)N1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 19/20 0.37
▸ EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12374471 0.88 FOLH1 (0.46) FOLH1
SCHEMBL22590698 0.83 TSHR (0.31) —
SCHEMBL23912613 0.81 — —
SCHEMBL22590666 0.80 — —
SCHEMBL12374474 0.80 ABL1 (0.37) FOLH1
SCHEMBL21065266 0.79 TDP1 (0.43) —
SCHEMBL21065264 0.79 TDP1 (0.43) —
SCHEMBL23912615 0.79 — —
SCHEMBL12462486 0.77 FOLH1 (0.45) FOLH1
SCHEMBL12374495 0.75 FOLH1 (0.33) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11141368-B2 Cosmetic composition, cosmetic treatment method, kit, and compound L'OREAL (FR) 2021-10-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11141368-B2 Cosmetic composition, cosmetic treatment method, kit, and compound KRT18, KIT, TYR FOLH1 2171/4885EPHX2 971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback