Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374471 | 0.86 | FOLH1 (0.46) | FOLH1ABL1 | |
| SCHEMBL12462492 | 0.85 | ABL1 (0.39) | METCDK9ABL1 | |
| SCHEMBL15368058 | 0.82 | CA1 (0.46) | FOLH1HDAC1HDAC6SIRT1CA1 | |
| SCHEMBL12462231 | 0.82 | SIRT6 (0.36) | HDAC1HDAC6SIRT6SIRT1ABL1 | |
| SCHEMBL12374497 | 0.81 | MEN1 (0.45) | FOLH1HDAC1HDAC6SIRT1ABL1 | |
| SCHEMBL12374475 | 0.80 | HTT (0.34) | ABL1 | |
| SCHEMBL12407949 | 0.80 | SIRT5 (0.40) | FOLH1HDAC1HDAC6SIRT1CA1 | |
| SCHEMBL12374476 | 0.78 | ABL1 (0.33) | ABL1 | |
| SCHEMBL11988265 | 0.78 | ABL1 (0.33) | METABL1ROCK2 | |
| SCHEMBL12462225 | 0.78 | ABL1 (0.35) | HDAC1HDAC6ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575341-B2 | Cosmetic composition, cosmetic treatment method, and compound | L'OREAL (FR) | 2013-11-05 | — | — | US | disclosed |
| US-8575341-B2 | Cosmetic composition, cosmetic treatment method, and compound | L'OREAL (FR) | 2013-11-05 | — | — | US | disclosed |
| US-20110189118-A1 | COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, AND COMPOUND | L'OREAL (FR) | 2011-08-04 | — | — | US | disclosed |
| US-20110189118-A1 | COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, AND COMPOUND | L'OREAL (FR) | 2011-08-04 | — | — | US | disclosed |
| WO-2011083243-A1 | COSMETIC TREATMENT METHODS AND KIT | L'OREAL (FR) | 2011-07-14 | — | — | WO | disclosed |
| WO-2010001041-A2 | COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, AND COMPOUND | L'OREAL (FR) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189118-A1 | COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, AND COMPOUND | KRT18, MC1R, C1R | FOLH1 2378/4885HDAC1 62/4885HDAC6 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.