Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15351663 | 0.89 | CYP2C9 (0.51) | HTTALDH1A1MAPK1NPC1TP53 | |
| SCHEMBL21102374 | 0.88 | ALDH1A1 (0.49) | HTTALDH1A1MAPK1NPC1TP53 | |
| SCHEMBL519387 | 0.87 | CYP2C9 (0.56) | HTTLMNAALDH1A1MAPK1NPC1 | |
| SCHEMBL20613721 | 0.85 | ALDH1A1 (0.47) | HTTALDH1A1MAPK1NPC1TP53 | |
| SCHEMBL31338988 | 0.83 | NNMT (0.42) | HTTLMNAALDH1A1MAPK1MAPT | |
| SCHEMBL31338984 | 0.83 | NNMT (0.42) | HTTLMNAALDH1A1MAPK1MAPT | |
| SCHEMBL17986785 | 0.82 | ALDH1A1 (0.44) | HTTALDH1A1MAPK1NPC1TP53 | |
| SCHEMBL17173720 | 0.81 | MAPT (0.51) | HTTALDH1A1MAPK1NPC1TP53 | |
| SCHEMBL6492223 | 0.81 | MAPT (0.51) | HTTALDH1A1MAPK1NPC1TP53 | |
| SCHEMBL14831259 | 0.81 | ALDH1A1 (0.51) | HTTALDH1A1MAPK1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564238-B1 | FUSED HETEROCYCLIC COMPOUND HAVING OXIME GROUP OR SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUNDS, AND METHOD FOR USING SAID INSECTICIDE | NIHON NOHYAKU CO LTD (JP) | 2021-10-13 | — | — | EP | disclosed |