Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | GLP1R | P43220 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15351663 | 0.91 | CYP2C9 (0.51) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 | |
| SCHEMBL21102374 | 0.89 | ALDH1A1 (0.49) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 | |
| SCHEMBL15449653 | 0.88 | CYP2C9 (0.56) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 | |
| SCHEMBL23912583 | 0.87 | HTT (0.48) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 | |
| SCHEMBL20613721 | 0.87 | ALDH1A1 (0.47) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 | |
| SCHEMBL10269771 | 0.84 | CYP2C19 (0.59) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 | |
| SCHEMBL17986785 | 0.83 | ALDH1A1 (0.44) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 | |
| SCHEMBL17173720 | 0.83 | MAPT (0.51) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 | |
| SCHEMBL6492223 | 0.83 | MAPT (0.51) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 | |
| SCHEMBL8883897 | 0.83 | KDM4E (0.47) | CYP2C9CYP2C19ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787809-B2 | Oxime group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2023-10-17 | — | — | US | disclosed |
| US-11787809-B2 | Oxime group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2023-10-17 | — | — | US | disclosed |
| US-11787809-B2 | Oxime group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2023-10-17 | — | — | US | disclosed |
| EP-3372595-B1 | OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALTS THEREOF AND AGRICULTURAL AND HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | NIHON NOHYAKU CO LTD (JP) | 2023-06-28 | — | — | EP | disclosed |
| US-20230025249-A1 | PROCESS FOR THE PREPARATION OF 5-CHLORO-PYRIDINE-2-CARBOXYLIC ACIDS AND CARBOXYLATES WITH 3-SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-26 | — | — | US | disclosed |
| CN-110114354-B | Condensed heterocyclic compound having oxime group or salt thereof, agricultural and horticultural insecticide containing the same, and method of using the same | 日本农药株式会社 | 2022-04-29 | — | — | CN | disclosed |
| US-11208410-B2 | Heterocycle-bound condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2021-12-28 | — | — | US | disclosed |
| US-20210371424-A1 | OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| US-20210371424-A1 | OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| CN-109415357-B | Condensed heterocyclic compound having hydrazone group or salt thereof, agricultural and horticultural insecticide containing the compound, and method for using the same | 日本农药株式会社 | 2021-10-29 | — | — | CN | disclosed |
| US-20130267701-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | MIDCAP FINANCIAL TRUST | 2013-10-10 | — | — | US | disclosed |
| US-20130267701-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | MIDCAP FINANCIAL TRUST | 2013-10-10 | — | — | US | disclosed |
| US-20130203987-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | RIGEL PHARMACEUTICALS, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130203987-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | RIGEL PHARMACEUTICALS, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130203987-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | RIGEL PHARMACEUTICALS, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| EP-2598483-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | Rigel Pharmaceuticals, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| US-20120028954-A1 | Substituted Pyridine, Pyridazine, Pyrazine And Pyrimidine Compounds And Methods For Using The Same | RIGEL PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120028954-A1 | Substituted Pyridine, Pyridazine, Pyrazine And Pyrimidine Compounds And Methods For Using The Same | RIGEL PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2012016217-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | RIGEL PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012016217-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | RIGEL PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028954-A1 | Substituted Pyridine, Pyridazine, Pyrazine And Pyrimidine Compounds And Methods For Using The Same | AK2, PC, PRKAG2 | CYP2C9 2629/4885CYP2C19 1636/4885ALDH1A1 1146/4885 |
| US-20210371424-A1 | OXIME GROUP-CONTAINING CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | DDT, OXSR1, ODC1 | CYP2C9 32/4885CYP2C19 175/4885ALDH1A1 1027/4885 |
| US-11787809-B2 | Oxime group-containing condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | DDT, OXSR1, ODC1 | CYP2C9 32/4885CYP2C19 175/4885ALDH1A1 1027/4885 |
| US-20230025249-A1 | PROCESS FOR THE PREPARATION OF 5-CHLORO-PYRIDINE-2-CARBOXYLIC ACIDS AND CARBOXYLATES WITH 3-SULFUR CONTAINING SUBSTITUENTS | CPS1, SDHA, CYP2S1 | CYP2C9 59/4885CYP2C19 136/4885ALDH1A1 62/4885 |
| US-20130203987-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | PRKAG1, PRKAG2, PRKAB1 | CYP2C9 2914/4885CYP2C19 2229/4885ALDH1A1 807/4885 |
| US-20130267701-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | PRKAG1, PRKAG2, PRKAB1 | CYP2C9 2914/4885CYP2C19 2229/4885ALDH1A1 807/4885 |
| US-11208410-B2 | Heterocycle-bound condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | HDHD5, H1-0, H1-3 | CYP2C9 484/4885CYP2C19 769/4885ALDH1A1 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.