Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 12/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912819 | 0.90 | PIK3C3 (0.34) | PIK3C3NPC1 | |
| SCHEMBL23912736 | 0.87 | PIK3C3 (0.32) | PIK3C3MAPK14NPC1ALDH1A1 | |
| SCHEMBL23912821 | 0.84 | PIK3C3 (0.36) | PIK3C3MAPK14ALOX15 | |
| SCHEMBL23912723 | 0.80 | HPGD (0.33) | PIK3C3ALDH1A1 | |
| SCHEMBL23912714 | 0.77 | PIK3C3 (0.36) | PIK3C3NPC1ALDH1A1 | |
| SCHEMBL23912816 | 0.77 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL16913757 | 0.76 | PIK3C3 (0.56) | PIK3C3NPC1ALDH1A1 | |
| SCHEMBL20924105 | 0.75 | NPC1 (0.38) | MAPK14ALOX15NPC1ALDH1A1MAPK11 | |
| SCHEMBL23912807 | 0.75 | AR (0.41) | PIK3C3 | |
| SCHEMBL16913865 | 0.74 | PIK3C3 (0.58) | PIK3C3PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |