Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912819 | 0.85 | PIK3C3 (0.34) | HPGDPIK3C3 | |
| SCHEMBL23912815 | 0.80 | PIK3C3 (0.34) | ALDH1A1PIK3C3 | |
| SCHEMBL23912714 | 0.77 | PIK3C3 (0.36) | ALDH1A1HTTPIK3C3 | |
| SCHEMBL23912807 | 0.77 | AR (0.41) | PIK3C3 | |
| SCHEMBL16996875 | 0.73 | EDNRB (0.53) | HPGDALDH1A1MAPTHTTPIK3C3 | |
| SCHEMBL16926832 | 0.70 | MAOB (0.36) | ALDH1A1PIK3C3 | |
| SCHEMBL16913924 | 0.68 | PIK3C3 (0.39) | ALDH1A1HTTPIK3C3 | |
| SCHEMBL22695577 | 0.67 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL16926599 | 0.66 | PIK3C3 (0.57) | PIK3C3 | |
| SCHEMBL23912736 | 0.66 | PIK3C3 (0.32) | ALDH1A1PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |