Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16926832 | 0.83 | MAOB (0.36) | ARPIK3C3 | |
| SCHEMBL23912714 | 0.79 | PIK3C3 (0.36) | KMT2APIK3C3MEN1L3MBTL1 | |
| SCHEMBL23912723 | 0.77 | HPGD (0.33) | PIK3C3 | |
| SCHEMBL16926833 | 0.76 | PIK3C3 (0.59) | PIK3C3PPARGCYP3A4 | |
| SCHEMBL23912819 | 0.75 | PIK3C3 (0.34) | PIK3C3 | |
| SCHEMBL23912815 | 0.75 | PIK3C3 (0.34) | PIK3C3 | |
| SCHEMBL16996869 | 0.70 | PIK3C3 (0.56) | PIK3C3 | |
| SCHEMBL16913924 | 0.64 | PIK3C3 (0.39) | PIK3C3 | |
| SCHEMBL4410595 | 0.64 | AR (0.58) | ARKMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL22695577 | 0.63 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |