Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912807 | 0.79 | AR (0.41) | PIK3C3MEN1KMT2AL3MBTL1 | |
| SCHEMBL23912815 | 0.77 | PIK3C3 (0.34) | PIK3C3ALDH1A1NPC1 | |
| SCHEMBL23912819 | 0.77 | PIK3C3 (0.34) | PIK3C3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23912723 | 0.77 | HPGD (0.33) | PIK3C3ALDH1A1HTT | |
| SCHEMBL16926600 | 0.76 | PIK3C3 (0.59) | PIK3C3ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL20256180 | 0.68 | PDE2A (0.42) | ALDH1A1PDE2A | |
| SCHEMBL16926832 | 0.66 | MAOB (0.36) | PIK3C3ALDH1A1 | |
| SCHEMBL15410199 | 0.65 | IKBKB (0.45) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL23912736 | 0.64 | PIK3C3 (0.32) | PIK3C3ALDH1A1NPC1GAA | |
| SCHEMBL16913924 | 0.64 | PIK3C3 (0.39) | PIK3C3ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |