SCHEMBL23912860

SCHEMBL23912860

CC1CC2CC(C)CC(NC(=O)N3CC(OC(c4ccc(F)cc4)c4ccccc4C(F)(F)F)C3)(C1)C2

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.39
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
CNR2 P34972 1/20 0.37
MGLL Q99685 1/20 0.35
ABHD6 Q9BV23 1/20 0.35
RBP4 P02753 1/20 0.35
HPGD P15428 1/20 0.35
EPHX2 P34913 2/20 0.34
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4084890 0.94 CNR2 (0.43) FAAHLMNAHTTCNR2MGLL
SCHEMBL23912886 0.93 CNR2 (0.37) FAAHLMNAHTTCNR2RBP4
SCHEMBL23912846 0.93 FAAH (0.43) FAAH
SCHEMBL23912872 0.92 LMNA (0.43) FAAHLMNAHTTCNR2RBP4
SCHEMBL23912845 0.91 EPHX2 (0.36) FAAHLMNAHTTCNR2RBP4
SCHEMBL4075700 0.88 CNR2 (0.42) FAAHLMNAHTTCNR2HPGD
SCHEMBL24454993 0.87 TACR1 (0.40) FAAHLMNAHTTCNR2MGLL
SCHEMBL4085241 0.86 LMNA (0.48) FAAHLMNAHTTCNR2RBP4
SCHEMBL4075138 0.86 FAAH (0.43) FAAHLMNAHTTCNR2MGLL
SCHEMBL4075602 0.86 EPHX2 (0.40) LMNAHTTCNR2HPGDEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220151990-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE ANEBULO PHARMACEUTICALS, INC. 2022-05-19 US disclosed
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose ANEBULO PHARMACEUTICALS, INC. (US) 2021-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220151990-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE CNR1, CNR2, FAAH FAAH 3/4885LMNA 2773/4885HTT 1596/4885
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose CNR1, CNR2, FAAH FAAH 3/4885LMNA 2773/4885HTT 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.