SCHEMBL23912872

SCHEMBL23912872

COc1ccc(C(OC2CN(C(=O)NC34CC(C)CC(CC(C)C3)C4)C2)c2ccccc2C(F)(F)F)cc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
GAA P10253 1/20 0.43
FAAH O00519 4/20 0.40
HTT P42858 1/20 0.38
CNR2 P34972 3/20 0.38
EPHX2 P34913 3/20 0.37
RBP4 P02753 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
SLC6A9 P48067 1/20 0.36
NPSR1 Q6W5P4 2/20 0.35
ALDH1A1 P00352 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4085241 0.95 LMNA (0.48) LMNAGAAFAAHHTTCNR2
SCHEMBL23912860 0.92 FAAH (0.39) LMNAFAAHHTTCNR2EPHX2
SCHEMBL23912886 0.92 CNR2 (0.37) LMNAGAAFAAHHTTCNR2
SCHEMBL23912846 0.91 FAAH (0.43) FAAH
SCHEMBL23912845 0.90 EPHX2 (0.36) LMNAGAAFAAHHTTCNR2
SCHEMBL4075700 0.87 CNR2 (0.42) LMNAGAAFAAHHTTCNR2
SCHEMBL4084890 0.86 CNR2 (0.43) LMNAFAAHHTTCNR2EPHX2
SCHEMBL4075138 0.85 FAAH (0.43) LMNAFAAHHTTCNR2CYP2C19
SCHEMBL4075602 0.84 EPHX2 (0.40) LMNAGAAHTTCNR2EPHX2
SCHEMBL23912873 0.84 FAAH (0.40) FAAHEPHX2RBP4CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022109043-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE ANEBULO PHARMACEUTICALS, INC. (US) 2022-05-27 WO disclosed
US-20220151990-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE ANEBULO PHARMACEUTICALS, INC. 2022-05-19 US disclosed
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose ANEBULO PHARMACEUTICALS, INC. (US) 2021-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220151990-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE CNR1, CNR2, FAAH LMNA 2773/4885GAA 2900/4885FAAH 3/4885
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose CNR1, CNR2, FAAH LMNA 2773/4885GAA 2900/4885FAAH 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.