Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 19/20 | 0.39 |
| ▸ | ITGB6 | P18564 | 15/20 | 0.39 |
| ▸ | ITGB8 | P26012 | 13/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 12/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156283 | 0.94 | ITGB3 (0.38) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL20156034 | 0.90 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL20156250 | 0.87 | ITGAV (0.52) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL20156282 | 0.83 | ITGB3 (0.57) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL20156366 | 0.81 | ITGAV (0.59) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL20156251 | 0.80 | ITGAV (0.50) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL20156083 | 0.78 | ITGB3 (0.40) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL20156278 | 0.77 | WDR5 (0.32) | — | |
| SCHEMBL20156279 | 0.76 | SUCNR1 (0.37) | ITGAVITGB3 | |
| SCHEMBL20156363 | 0.76 | ITGB3 (0.38) | ITGAVITGB3ITGB6ITGB8ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |