Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23915196 | 0.96 | S1PR2 (0.33) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23914615 | 0.93 | S1PR2 (0.37) | S1PR2 | |
| SCHEMBL23914723 | 0.93 | PGR (0.33) | PGRS1PR2PIK3CDCYP1A2CYP3A4 | |
| SCHEMBL23915609 | 0.89 | ADRA1A (0.36) | S1PR2CYP3A4 | |
| SCHEMBL23908980 | 0.88 | S1PR2 (0.34) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23914613 | 0.86 | S1PR2 (0.37) | S1PR2 | |
| SCHEMBL23914614 | 0.85 | HRH1 (0.36) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23915420 | 0.84 | S1PR2 (0.33) | S1PR2 | |
| SCHEMBL23915442 | 0.84 | S1PR2 (0.35) | S1PR2 | |
| SCHEMBL23966827 | 0.82 | S1PR2 (0.36) | PGRS1PR2PIK3CDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GILEAD SCIENCES, INC. | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | S1PR1, S1PR3, S1PR2 | PGR 1866/4885S1PR2 3/4885PIK3CD 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.