Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908980 | 0.86 | S1PR2 (0.34) | S1PR2L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23915196 | 0.86 | S1PR2 (0.33) | S1PR2L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23966551 | 0.85 | S1PR2 (0.37) | S1PR2 | |
| SCHEMBL23966573 | 0.83 | BTK (0.35) | S1PR2PIK3CD | |
| SCHEMBL23914723 | 0.82 | PGR (0.33) | S1PR2L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23914725 | 0.82 | PGR (0.32) | S1PR2L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23915356 | 0.79 | S1PR2 (0.39) | S1PR2 | |
| SCHEMBL23966577 | 0.78 | S1PR2 (0.38) | S1PR2 | |
| SCHEMBL23966578 | 0.76 | S1PR2 (0.44) | S1PR2 | |
| SCHEMBL23908868 | 0.75 | S1PR2 (0.61) | S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |