SCHEMBL7541462

SCHEMBL7541462

CN(C)c1ccc(C(c2ccc(N(C)C)cc2)c2c(F)cccc2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.47
MAT2A P31153 1/20 0.47
SLC2A1 P11166 1/20 0.47
TSHR P16473 5/20 0.43
MAPK1 P28482 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
CYP3A4 P08684 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CYP1A2 P05177 1/20 0.43
MAPT P10636 1/20 0.43
PHLPP2 Q6ZVD8 1/20 0.43
ALDH1A1 P00352 8/20 0.42
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
GAA P10253 2/20 0.39
NQO1 P15559 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KMT2A Q03164 2/20 0.39
RXFP1 Q9HBX9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7540779 0.80 SLC2A1 (0.50) SLC2A1TSHRMAPK1TDP1CYP3A4
SCHEMBL2391501 0.79 SLC2A1 (0.46) KCNH2MAT2ASLC2A1TSHRMAPK1
SCHEMBL4711046 0.77 GAA (0.40) ALDH1A1GAAKMT2A
SCHEMBL6556826 0.77 SLC2A1 (0.47) SLC2A1TSHRMAPK1TDP1CYP3A4
SCHEMBL28264167 0.76 ALDH1A1 (0.46) KCNH2MAT2ATSHRMAPK1L3MBTL1
SCHEMBL9626237 0.76 SLC2A1 (0.71) SLC2A1TSHRMAPK1TDP1CYP3A4
SCHEMBL61574 0.76 SLC2A1 (0.71) SLC2A1TSHRMAPK1TDP1CYP3A4
SCHEMBL7536675 0.74 KMT2A (0.51) KCNH2MAT2ASLC2A1TSHRMAPK1
SCHEMBL14594215 0.74 ALDH1A1 (0.48) KCNH2MAT2ASLC2A1TSHRMAPK1
SCHEMBL7110610 0.73 SLC2A1 (0.61) SLC2A1TSHRMAPK1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6479217-B1 PHOTOSENSITIVE RECORDING; APPLYING ACTINIC RADIATION; PHOTOPOLYMERIZATION SPECTRA GROUP LIMITED, INC. 2002-11-12 US disclosed
US-20020160310-A1 Method for producing selectively colorable printing plates SPECTRA GROUP LIMITED, INC. 2002-10-31 US disclosed
US-6433035-B1 LEUCO DYE OR DI-, TRI- OR MONOARYLMETHANE DYE COLOR FORMERS YIELD CATIONIC DYE WHEN EXPOSED TO ACTINIC RADIATION IN PRESENCE OF OXIDIZER; BLEACHING AT HIGHER DOSAGES; CURING SPECTRA GROUP LIMITED, INC. 2002-08-13 US disclosed
US-6309797-B1 CONTAINING OXIDIZER; EXPOSURE TO ACTINIC RADIATION SPECTRA GROUP LIMITED, INC. 2001-10-30 US disclosed