Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22074019 | 0.79 | ALDH1A1 (0.41) | EGFRERBB2MEN1HSP90AA1KMT2A | |
| SCHEMBL6136949 | 0.71 | LMNA (0.51) | EGFRERBB2MEN1HSP90AA1KMT2A | |
| SCHEMBL6136951 | 0.71 | LMNA (0.51) | EGFRERBB2MEN1HSP90AA1KMT2A | |
| SCHEMBL949756 | 0.70 | SRD5A2 (0.52) | EGFRERBB2MEN1HSP90AA1KMT2A | |
| SCHEMBL949755 | 0.70 | SRD5A2 (0.52) | EGFRERBB2MEN1HSP90AA1KMT2A | |
| SCHEMBL13791103 | 0.69 | KDM4E (0.56) | MEN1HSP90AA1KMT2ANR1H4ALDH1A1 | |
| SCHEMBL16319026 | 0.69 | MEN1 (0.53) | MEN1HSP90AA1KMT2ANPC1RAB9A | |
| SCHEMBL16319027 | 0.69 | MEN1 (0.53) | MEN1HSP90AA1KMT2ANPC1RAB9A | |
| SCHEMBL6539315 | 0.68 | GSK3B (0.68) | EGFRERBB2MEN1KMT2ANPC1 | |
| SCHEMBL6539306 | 0.68 | GSK3B (0.68) | EGFRERBB2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892616-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |