Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23916378 | 0.73 | — | — | |
| SCHEMBL27876719 | 0.67 | KMT2A (0.38) | — | |
| SCHEMBL24092520 | 0.66 | CRHR1 (0.42) | S1PR1S1PR3HCAR3CRHR1AR | |
| SCHEMBL25456825 | 0.63 | ATG4B (0.36) | CRHR1AR | |
| SCHEMBL25925332 | 0.63 | AGTR1 (0.36) | HCAR3CRHR1 | |
| SCHEMBL3347417 | 0.62 | AR (0.48) | AR | |
| SCHEMBL23839470 | 0.62 | AR (0.48) | S1PR1S1PR3HCAR3CRHR1AR | |
| SCHEMBL18655174 | 0.62 | CNR1 (0.32) | CRHR1 | |
| SCHEMBL24092707 | 0.62 | CRHR1 (0.40) | HCAR3CRHR1 | |
| SCHEMBL13659896 | 0.61 | CRHR1 (0.46) | S1PR1S1PR3HCAR3CRHR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892276-A1 | ISOQUINOLIN-3-YL CARBOXAMIDES AS WNT INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |