Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.57 |
| ▸ | WNT1 | P04628 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19546661 | 0.82 | QDPR (0.41) | QDPRWNT1GSK3BDYRK1A | |
| SCHEMBL23048767 | 0.82 | WNT1 (0.41) | QDPRWNT1GSK3BDYRK1A | |
| SCHEMBL20950816 | 0.81 | JMJD6 (0.55) | WNT1GSK3BDYRK1A | |
| SCHEMBL23916632 | 0.81 | QDPR (0.40) | QDPRWNT1GSK3BDYRK1A | |
| SCHEMBL23048820 | 0.80 | DYRK1A (0.51) | QDPRWNT1GSK3BDYRK1A | |
| SCHEMBL21037757 | 0.80 | SCN9A (0.41) | QDPRWNT1GSK3BDYRK1A | |
| SCHEMBL23048814 | 0.80 | QDPR (0.41) | QDPRWNT1GSK3BDYRK1A | |
| SCHEMBL8488039 | 0.78 | SIGMAR1 (0.53) | QDPR | |
| SCHEMBL20950324 | 0.76 | DYRK1A (0.48) | WNT1GSK3BDYRK1A | |
| SCHEMBL19035702 | 0.74 | QDPR (0.44) | QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892276-A1 | ISOQUINOLIN-3-YL CARBOXAMIDES AS WNT INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |