Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | CHKA | P35790 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611760 | 0.92 | FAAH (0.63) | FAAHPRMT6SIGMAR1NPC1RAB9A | |
| SCHEMBL19066596 | 0.92 | FAAH (0.63) | FAAHPRMT6SIGMAR1NPC1RAB9A | |
| SCHEMBL19066585 | 0.86 | FAAH (0.57) | FAAHLMNASIGMAR1NPC1RAB9A | |
| SCHEMBL30889265 | 0.85 | PRMT6 (0.57) | FAAHHRH3PRMT6 | |
| SCHEMBL610620 | 0.85 | PRMT6 (0.57) | FAAHHRH3PRMT6 | |
| SCHEMBL209815 | 0.84 | MC4R (0.57) | MC4RFAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL31528202 | 0.84 | MC4R (0.57) | MC4RFAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL609148 | 0.84 | SMN1; SMN2 (0.58) | FAAHHRH3PRMT6 | |
| SCHEMBL817090 | 0.84 | SMN1; SMN2 (0.58) | FAAHHRH3PRMT6 | |
| SCHEMBL12126807 | 0.83 | MC4R (0.56) | MC4RHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892276-A1 | ISOQUINOLIN-3-YL CARBOXAMIDES AS WNT INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |