SCHEMBL610620

SCHEMBL610620

C=Cc1cccc(CN2CCCC2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.57
FAAH O00519 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
ALDH1A1 P00352 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
KDM4E B2RXH2 1/20 0.51
GAA P10253 1/20 0.51
CYP2D6 P10635 2/20 0.50
CYP2C9 P11712 1/20 0.50
HIF1A Q16665 1/20 0.50
CYP2C19 P33261 1/20 0.47
HRH3 Q9Y5N1 3/20 0.47
MBTD1 Q05BQ5 1/20 0.46
TP53BP1 Q12888 1/20 0.46
L3MBTL3 Q96JM7 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ACHE P22303 1/20 0.45
POLB P06746 1/20 0.45
CHRNB2 P17787 1/20 0.45
CHRNA4 P43681 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30889265 1.00 PRMT6 (0.57) PRMT6FAAHSMN1; SMN2ALDH1A1TDP1
SCHEMBL817090 0.98 SMN1; SMN2 (0.58) PRMT6FAAHSMN1; SMN2ALDH1A1TDP1
SCHEMBL609148 0.98 SMN1; SMN2 (0.58) PRMT6FAAHSMN1; SMN2ALDH1A1TDP1
SCHEMBL611760 0.93 FAAH (0.63) PRMT6FAAHSMN1; SMN2ALDH1A1TDP1
SCHEMBL19066596 0.93 FAAH (0.63) PRMT6FAAHSMN1; SMN2ALDH1A1TDP1
SCHEMBL19066585 0.87 FAAH (0.57) FAAHALDH1A1KDM4EGAACYP2D6
SCHEMBL23916559 0.85 MC4R (0.57) PRMT6FAAHHRH3
SCHEMBL19066609 0.85 SIGMAR1 (0.57) PRMT6FAAHALDH1A1TDP1CYP2C9
SCHEMBL5673597 0.85 NCF1 (0.60) FAAHSMN1; SMN2ALDH1A1KDM4EHIF1A
Hydrochloric Acid SCHEMBL9051088 0.84 SIGMAR1 (0.56) FAAHTDP1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107743498-B Initiator for copolymerization of diene monomer and vinyl aromatic monomer 西索斯公司 2020-04-28 CN claimed
US-10584187-B2 Initiators for the copolymerisation of diene monomers and vinyl aromatic monomers SYNTHOS S.A. (PL) 2020-03-10 US claimed
EP-3280745-B1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS Synthos Sa (PL) 2018-12-12 EP claimed
US-20180072821-A1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS SYNTHOS S.A. (PL) 2018-03-15 US claimed
CN-107743498-A Initiator for copolymerization of diene monomer and vinyl aromatic monomer 西索斯公司 2018-02-27 CN claimed
EP-3280745-A1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS Synthos S.A. (PL) 2018-02-14 EP claimed
WO-2016162482-A1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS SYNTHOS S.A. (PL) 2016-10-13 WO claimed
CN-107743498-B Initiator for copolymerization of diene monomer and vinyl aromatic monomer 西索斯公司 2020-04-28 CN disclosed
EP-3239183-B1 MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER SUMITOMO CHEMICAL CO (JP) 2020-03-11 EP disclosed
US-10584187-B2 Initiators for the copolymerisation of diene monomers and vinyl aromatic monomers SYNTHOS S.A. (PL) 2020-03-10 US disclosed
EP-3280745-B1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS Synthos Sa (PL) 2018-12-12 EP disclosed
US-10118973-B2 Modified conjugated diene polymer, and polymer composition containing said polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-11-06 US disclosed
US-20180072821-A1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS SYNTHOS S.A. (PL) 2018-03-15 US disclosed
US-6753447-B2 REACTING SECONDARY AMINE WITH 2,3- DIHALOPROPENE TO PRODUCE A VINYL HALIDE CONTAINING CYCLIC TERTIARY AMINE; REACTING WITH VINYL MAGNESIUM HALIDE IN POLAR SOLVENT THE GOODYEAR TIRE & RUBBER COMPANY 2004-06-22 US disclosed
US-20040116635-A1 Functionalized monomers for synthesis of rubbery polymers GOODYEAR TIRE & RUBBER COMPANY, THE 2004-06-17 US disclosed
US-20040063884-A1 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY 2004-04-01 US disclosed
US-20040048972-A1 Functionalized monomers for synthesis of rubbery polymers GOODYEAR TIRE & RUBBER COMPANY, THE 2004-03-11 US disclosed
US-20040044157-A1 Functionalized monomers for synthesis of rubbery polymers GOODYEAR TIRE & RUBBER COMPANY, THE 2004-03-04 US disclosed
US-20040044202-A1 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY 2004-03-04 US disclosed
US-6693160-B1 FREE RADICAL COPOLYMERS OF CONJUGATED DIOLEFIN AND NITROGEN HETEROCYCLE FUNCTIONALIZED MONOMERS; LOW HYSTERESIS; FILLER COMPATIBILITY THE GOODYEAR TIRE & RUBBER COMPANY 2004-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040044202-A1 Functionalized monomers for synthesis of rubbery polymers PRMT1, DDR2, DNMT3A PRMT6 18/4885FAAH 1566/4885SMN1; SMN2 2459/4885
US-20040063884-A1 Functionalized monomers for synthesis of rubbery polymers RDX, DPY30, RIF1 PRMT6 91/4885FAAH 2701/4885SMN1; SMN2 2557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.