Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.34 |
| ▸ | GSK3B | P49841 | 9/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 3/20 | 0.32 |
| ▸ | WNT1 | P04628 | 4/20 | 0.31 |
| ▸ | CLK2 | P49760 | 3/20 | 0.31 |
| ▸ | CLK3 | P49761 | 3/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23916195 | 0.84 | HCAR3 (0.36) | ABL1ACACBACACADYRK1AGSK3B | |
| SCHEMBL23741370 | 0.74 | HCAR3 (0.34) | ABL1ACACBACACADYRK1AGSK3B | |
| SCHEMBL23048827 | 0.72 | ACACB (0.33) | ABL1ACACBACACADYRK1AGSK3B | |
| SCHEMBL23741148 | 0.71 | HCAR3 (0.36) | ABL1ACACBACACADYRK1AGSK3B | |
| SCHEMBL2671513 | 0.71 | HCAR3 (0.60) | ACACBACACADYRK1AGSK3BHCAR3 | |
| SCHEMBL4137382 | 0.70 | NNMT (0.44) | ACACBACACADYRK1AGSK3BHCAR3 | |
| SCHEMBL24219443 | 0.69 | ACACB (0.35) | ABL1ACACBACACADYRK1AGSK3B | |
| SCHEMBL2671631 | 0.69 | ALOX15 (0.49) | DYRK1AGSK3BHCAR3NNMT | |
| SCHEMBL23048918 | 0.68 | HCAR3 (0.33) | ABL1ACACBACACADYRK1AGSK3B | |
| SCHEMBL4404906 | 0.68 | HCAR3 (0.44) | ABL1ACACBACACADYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892276-A1 | ISOQUINOLIN-3-YL CARBOXAMIDES AS WNT INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |