SCHEMBL2391723

SCHEMBL2391723

CCCCOc1nc(N)c2[nH]c(=O)n(CCSc3cc(OC(C)=O)ccc3C)c2n1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5522471 0.89 TLR7 (0.56) TLR7
SCHEMBL2391717 0.85 TLR7 (0.54) TLR7
SCHEMBL2389742 0.84 TLR7 (0.52) TLR7
SCHEMBL5964535 0.79 TLR7 (0.57) TLR7
SCHEMBL5964658 0.79 TLR7 (0.70) TLR7
SCHEMBL5523819 0.79 TLR7 (0.55) TLR7
SCHEMBL17473811 0.78 TLR7 (0.68) TLR7
SCHEMBL2388778 0.78 TLR7 (0.63) TLR7
SCHEMBL3360321 0.77 TLR7 (0.76) TLR7
SCHEMBL17473815 0.77 TLR7 (0.54) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8012964-B2 9-substituted 8-oxoadenine compound DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2011-09-06 US disclosed