Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.33 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383163 | 1.00 | NOS1 (0.33) | NOS1NOS3NOS2 | |
| SCHEMBL29543849 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL2332914 | 0.72 | NOS1 (0.33) | NOS1NOS3NOS2 | |
| SCHEMBL920381 | 0.72 | — | — | |
| SCHEMBL23917373 | 0.70 | MAPK14 (0.37) | — | |
| SCHEMBL7465174 | 0.70 | NOS1 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL26937469 | 0.68 | GPR3 (0.40) | — | |
| SCHEMBL4938 | 0.67 | NOS1 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL19999997 | 0.66 | RAB9A (0.36) | — | |
| SCHEMBL15679169 | 0.66 | MAPT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1733715-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative, a coupling agent and a heterocyclic direct dye | OREAL (FR) | 2010-01-27 | — | — | EP | claimed |
| US-7582121-B2 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one heterocyclic direct dye | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | claimed |
| US-20070006398-A1 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one heterocyclic direct dye | L'OREAL S.A. (FR) | 2007-01-11 | — | — | US | claimed |
| US-6326368-B1 | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2001-12-04 | — | — | US | claimed |
| EP-3938345-B1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | NOCION THERAPEUTICS INC (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20260116859-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-12589090-B2 | Compounds and methods for the treatment of degenerative disorders | AQUILUS PHARMACEUTICALS, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| US-20260060989-A1 | Charged Ion Channel Blockers And Methods For Use | NOCION THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| EP-4048747-B1 | SELF-STOPPING POLISHING COMPOSITION AND METHOD | CMC MAT LLC (US) | 2026-02-18 | — | — | EP | disclosed |
| US-12544357-B2 | Compositions and methods for the treatment of Plasmodium falciparum malaria | BROWN UNIVERSITY (US) | 2026-02-10 | — | — | US | disclosed |
| US-20250367283-A1 | MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT | TSINGHUA UNIVERSITY (CN) | 2025-12-04 | — | — | US | disclosed |
| US-20250270189-A1 | Ester Substituted Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2025-08-28 | — | — | US | disclosed |
| US-20090137566-A1 | Substituted Piperdines as Renin Inhibitors | EHARA TAKERU | 2009-05-28 | — | — | US | disclosed |
| US-7267925-B2 | Photosensitive composition and novel compound used therefor | FUJIFILM CORPORATION (JP) | 2007-09-11 | — | — | US | disclosed |
| US-7267925-B2 | Photosensitive composition and novel compound used therefor | FUJIFILM CORPORATION (JP) | 2007-09-11 | — | — | US | disclosed |
| US-20070140973-A1 | CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2007-06-21 | — | — | US | disclosed |
| EP-1399577-B1 | METHOD FOR PRODUCING L-AMINO ACIDS | SHOWA DENKO KK (JP) | 2007-02-07 | — | — | EP | disclosed |
| US-20070015087-A1 | Photosensitive composition | FUJI PHOTO FILM CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20070015087-A1 | Photosensitive composition | FUJI PHOTO FILM CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20070006398-A1 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one heterocyclic direct dye | L'OREAL S.A. (FR) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12544357-B2 | Compositions and methods for the treatment of Plasmodium falciparum malaria | PFN1, PFKP, FGB | NOS1 3077/4885NOS3 2582/4885NOS2 3498/4885 |
| US-20250367283-A1 | MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT | COASY, GGPS1, HMGCR | NOS1 3589/4885NOS3 3764/4885NOS2 3379/4885 |
| US-12589090-B2 | Compounds and methods for the treatment of degenerative disorders | CASP3, CASP10, CASP1 | NOS1 383/4885NOS3 42/4885NOS2 380/4885 |
| US-20090137566-A1 | Substituted Piperdines as Renin Inhibitors | REN, ACE, AGTR1 | NOS1 1303/4885NOS3 1638/4885NOS2 1787/4885 |
| US-20260060989-A1 | Charged Ion Channel Blockers And Methods For Use | TRPV1, TRPA1, TRPV2 | NOS1 840/4885NOS3 936/4885NOS2 741/4885 |
| US-20070006398-A1 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one heterocyclic direct dye | KRT18, DSP, DSG1 | NOS1 1283/4885NOS3 1503/4885NOS2 1647/4885 |
| US-20260116859-A1 | Charged Ion Channel Blockers and Methods for Use | OPRL1, TRPV1, SCN2B | NOS1 1200/4885NOS3 1006/4885NOS2 1344/4885 |
| US-20250270189-A1 | Ester Substituted Ion Channel Blockers and Methods for Use | TRPV1, TRPA1, TRPV2 | NOS1 1391/4885NOS3 932/4885NOS2 1145/4885 |
| US-20070140973-A1 | CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING | TNNI3, TNNT2, TNNC1 | NOS1 3199/4885NOS3 3015/4885NOS2 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.