Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21622713 | 0.90 | CDK4 (0.35) | CDK4CCND1AXLALKJAK2 | |
| SCHEMBL21622772 | 0.85 | AHR (0.46) | ALKALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL21622771 | 0.78 | ALDH1A1 (0.40) | CDK4CCND1AXLJAK2ALDH1A1 | |
| SCHEMBL21622770 | 0.75 | AHR (0.44) | ALKALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL17154708 | 0.74 | CDK4 (0.57) | CDK4CCND1AXLJAK2ALDH1A1 | |
| SCHEMBL19041639 | 0.74 | CDK4 (0.57) | CDK4CCND1AXLJAK2ALDH1A1 | |
| SCHEMBL3365890 | 0.74 | CDK4 (0.57) | CDK4CCND1AXLJAK2ALDH1A1 | |
| SCHEMBL149685 | 0.74 | CDK4 (0.57) | CDK4CCND1AXLJAK2ALDH1A1 | |
| SCHEMBL12001022 | 0.74 | CDK4 (0.57) | CDK4CCND1AXLJAK2ALDH1A1 | |
| SCHEMBL30300831 | 0.74 | CDK4 (0.57) | CDK4CCND1AXLJAK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-02-14 | — | — | US | disclosed |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | CDK4 3048/4885CCND1 2928/4885AXL 3097/4885 |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | CDK4 3048/4885CCND1 2928/4885AXL 3097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.