SCHEMBL2391794

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2393512	0.88	APP (0.47)	APPCES2CES1AKR1C3AKR1C2
	SCHEMBL2393640	0.82	MAPT (0.40)	CES2CES1AKR1C3AKR1C2AKR1C1
	SCHEMBL9890697	0.82	PSEN1 (0.44)	APPCES2CES1AKR1C3AKR1C2
	SCHEMBL2395609	0.81	PARP1 (0.41)	CES2CES1
	SCHEMBL2391614	0.80	APP (0.43)	APPCTSACNR1RXRARXRB
	SCHEMBL2393200	0.80	APP (0.43)	APPCTSACNR1RXRARXRB
	SCHEMBL2393198	0.80	APP (0.43)	APPCTSACNR1RXRARXRB
	SCHEMBL2395590	0.80	APP (0.42)	APPCHRM3CTSASCN9AGRM2
	SCHEMBL9890804	0.75	CES2 (0.42)	CES2CES1GRM2
	SCHEMBL29658770	0.71	CES2 (0.64)	CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.