SCHEMBL2395590

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2391614	0.90	APP (0.43)	APPKCNA5PDK2CTSAFGFR1
	SCHEMBL2393200	0.90	APP (0.43)	APPKCNA5PDK2CTSAFGFR1
	SCHEMBL2393198	0.90	APP (0.43)	APPKCNA5PDK2CTSAFGFR1
	SCHEMBL12202160	0.83	CTSA (0.38)	TRPM8CTSAMETSLC9A1GRM5
	SCHEMBL9890803	0.81	CHRM1 (0.46)	CHRM3SLC9A1
	SCHEMBL2393221	0.81	SLC9A1 (0.42)	FGFR1FGFR3SLC9A1
	SCHEMBL2391794	0.80	APP (0.50)	APPCHRM3GRM2CTSASCN9A
	SCHEMBL2393512	0.80	APP (0.47)	APPCHRM3CTSASCN9A
	SCHEMBL2395250	0.80	ALOX5AP (0.39)	APPTRPM8CHRM3
	SCHEMBL9890802	0.79	SLC6A4 (0.44)	GRM2SLC9A1SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.