Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.64 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NMT1 | P30419 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048872 | 0.85 | DEGS1 (0.61) | DDAH1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL3713301 | 0.85 | NPC1 (0.70) | DDAH1TGM2TDP1NMT1NPC1 | |
| SCHEMBL10666505 | 0.83 | NAPRT (0.55) | TGM2NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL8263524 | 0.83 | NAPRT (0.55) | TGM2NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL11053361 | 0.82 | TSHR (0.50) | DDAH1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL10716420 | 0.81 | TGM2 (0.59) | DDAH1TGM2TDP1NMT1KIF11 | |
| SCHEMBL10716411 | 0.81 | TGM2 (0.59) | DDAH1TGM2TDP1NMT1KIF11 | |
| SCHEMBL10716405 | 0.81 | TGM2 (0.59) | DDAH1TGM2TDP1NMT1KIF11 | |
| SCHEMBL11594969 | 0.80 | KMT2A (0.50) | DDAH1TGM2TDP1NPC1RAB9A | |
| SCHEMBL14578749 | 0.78 | NMT1 (0.85) | DDAH1TGM2TDP1NMT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |