Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048872 | 0.82 | DEGS1 (0.61) | TSHRNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL23918242 | 0.82 | DDAH1 (0.64) | TSHRNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL10666505 | 0.80 | NAPRT (0.55) | TSHRNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL8263524 | 0.80 | NAPRT (0.55) | TSHRNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL11594969 | 0.77 | KMT2A (0.50) | TSHRNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL11052788 | 0.75 | CYP3A4 (0.41) | GAAKMT2AMEN1LMNA | |
| SCHEMBL274924 | 0.75 | TSHR (0.79) | TSHRNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1837826 | 0.75 | PEPD (0.61) | TSHRNPC1GAASAE1UBA2 | |
| SCHEMBL11051647 | 0.75 | MEN1 (0.60) | RAB9AHTTKMT2APOLBMEN1 | |
| SCHEMBL16090136 | 0.75 | TSHR (0.67) | TSHRNPC1SMN1; SMN2HTTSAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161580-A | Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | claimed |
| US-4089845-A | Thermosetting mixtures which are stable on storage from polyimide and .beta. | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | claimed |
| US-4424336-A | Meat-curable mixture, which are stable on storage, of epoxide resin, 3-aminocrotonic acid derivatives and maleimide compound | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0012715-B1 | EPOXIDE RESIN/BETA-AMINOCROTONIC ACID DERIVATIVE COMPOSITIONS WHICH ARE HEAT CURABLE AND STABLE WHEN STORED, AND THE MANUFACTURE OF INSOLUBLE AND UNMELTABLE PLASTIC PRODUCTS THEREFROM | CIBA-GEIGY AG (CH) | 1982-12-08 | — | — | EP | disclosed |
| US-4360655-A | Heat-curable mixtures, which are stable on storage, of epoxide compounds β-aminocrotonic acid derivatives and polyamine | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4348511-A | POLYURETHANES MODIFIED WITH BETA-AMINOCROTONIC ACID DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| US-4291146-A | Heat-curable mixtures, which are stable on storage, of expoxide resins and β-aminocrotonic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |
| US-4284752-A | Process for producing crosslinked unsaturated polymers by reaction of .beta. | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| US-4161580-A | Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-4089845-A | Thermosetting mixtures which are stable on storage from polyimide and .beta. | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |