Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263524 | 1.00 | NAPRT (0.55) | NAPRTHSD17B10TGM2DEGS1PARP1 | |
| SCHEMBL11051647 | 0.87 | MEN1 (0.60) | HSD17B10TGM2PARP1PARP15PARP10 | |
| SCHEMBL5177141 | 0.85 | PARP1 (0.57) | NAPRTHSD17B10TGM2DEGS1PARP1 | |
| SCHEMBL7679084 | 0.84 | SMN1; SMN2 (0.67) | NAPRTHSD17B10TGM2DEGS1CYP1A2 | |
| SCHEMBL396577 | 0.84 | SMN1; SMN2 (0.67) | NAPRTHSD17B10TGM2DEGS1CYP1A2 | |
| SCHEMBL23918242 | 0.83 | DDAH1 (0.64) | TGM2EGFRMMP1MMP2MMP9 | |
| SCHEMBL11048872 | 0.83 | DEGS1 (0.61) | DEGS1MAOBMMP1MMP2MMP9 | |
| SCHEMBL11530335 | 0.82 | PTGS2 (0.63) | NAPRTHSD17B10TGM2DEGS1CYP1A2 | |
| SCHEMBL11530331 | 0.82 | PTGS2 (0.63) | NAPRTHSD17B10TGM2DEGS1CYP1A2 | |
| SCHEMBL3802207 | 0.81 | TGM2 (0.52) | NAPRTHSD17B10TGM2DEGS1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62249972-A | — | — | None | — | — | JP | disclosed |
| US-4788205-A | ANTAGONISTS OF PLATELET ACTIVATING FACTOR | PFIZER INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0258033-A2 | Dihydropyridine anti-allergic and anti-inflammatory agents | Pfizer Limited (GB) | 1988-03-02 | — | — | EP | disclosed |
| JP-S62249972-A | PYRIDINE-3-CARBOXAMIDE DERIVATIVE AND PLANT GROWTH RETARDANT | DAICEL CHEM IND LTD | 1987-10-30 | — | — | JP | disclosed |