Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723199 | 0.91 | SENP7 (0.57) | SENP7CASP3JAK3NPC1RAB9A | |
| SCHEMBL21793711 | 0.91 | SENP7 (0.57) | SENP7CASP3JAK3NPC1RAB9A | |
| SCHEMBL30723187 | 0.90 | SENP7 (0.58) | SENP7CASP3JAK3NPC1RAB9A | |
| SCHEMBL21793874 | 0.90 | SENP7 (0.58) | SENP7CASP3JAK3NPC1RAB9A | |
| SCHEMBL21793861 | 0.83 | KMT2A (0.56) | SENP7CASP3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30723192 | 0.83 | KMT2A (0.56) | SENP7CASP3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21793707 | 0.83 | SENP7 (0.62) | SENP7CASP3JAK3NPC1RAB9A | |
| SCHEMBL21793867 | 0.82 | SENP7 (0.64) | SENP7CASP3JAK3NPC1RAB9A | |
| SCHEMBL23908580 | 0.80 | SENP7 (0.62) | SENP7CASP3JAK3NPC1RAB9A | |
| SCHEMBL21793708 | 0.80 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317095-A1 | COMPOUNDS USEFUL AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317095-A1 | COMPOUNDS USEFUL AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS | SQSTM1, HSPA5, ATG7 | SENP7 3099/4885CASP3 2834/4885JAK3 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.