Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660715 | 0.73 | TRPV4 (0.42) | TRPV4 | |
| SCHEMBL29292229 | 0.70 | AURKA (0.32) | — | |
| SCHEMBL17110437 | 0.70 | TRPV4 (0.38) | TRPV4MGLL | |
| SCHEMBL22087196 | 0.70 | MGLL (0.34) | TRPV4MGLLALOX15 | |
| SCHEMBL22085787 | 0.69 | TRPV4 (0.40) | TRPV4MGLLALOX15 | |
| SCHEMBL17110225 | 0.69 | TRPV4 (0.35) | TRPV4MGLL | |
| SCHEMBL17110223 | 0.69 | TRPV4 (0.35) | TRPV4MGLL | |
| SCHEMBL23134831 | 0.67 | P2RY12 (0.36) | TRPV4MGLLALOX15 | |
| SCHEMBL16654350 | 0.67 | NOTUM (0.38) | TRPV4MGLL | |
| SCHEMBL21816121 | 0.66 | NOTUM (0.49) | TRPV4MGLLALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892623-A1 | COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF | Korea Research Institute of Chemical Technology (KR) | 2021-10-13 | — | — | EP | disclosed |