Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389633 | 0.86 | CYP3A4 (0.48) | MAOBFDPSALOX5CYP3A4DPP4 | |
| SCHEMBL6023981 | 0.84 | KDM4E (0.68) | KDM4EHTR1AALDH1A1HPGDHTR2C | |
| SCHEMBL6023979 | 0.84 | KDM4E (0.68) | KDM4EHTR1AALDH1A1HPGDHTR2C | |
| SCHEMBL2391253 | 0.84 | CYP3A4 (0.46) | MAOBFDPSALOX5KDM4EALDH1A1 | |
| SCHEMBL8772838 | 0.83 | MAOB (0.68) | MAOBFDPSALOX5KDM4EHTR1A | |
| SCHEMBL8772845 | 0.83 | MAOB (0.68) | MAOBFDPSALOX5KDM4EHTR1A | |
| SCHEMBL2390189 | 0.80 | TTR (0.52) | MAOBFDPSALOX5CYP3A4DPP4 | |
| SCHEMBL2392289 | 0.78 | KDM4E (0.52) | MAOBFDPSALOX5KDM4EALDH1A1 | |
| SCHEMBL27537154 | 0.78 | KDM4E (0.52) | MAOBFDPSALOX5KDM4EALDH1A1 | |
| SCHEMBL2391351 | 0.78 | TTR (0.50) | MAOBFDPSALOX5ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |