Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695861 | 0.78 | CRHBP (0.34) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL15833136 | 0.69 | — | — | |
| SCHEMBL8607450 | 0.69 | — | — | |
| SCHEMBL20976299 | 0.68 | CRHBP (0.37) | CRHBPCRHR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL15740515 | 0.66 | ALDH1A1 (0.35) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL2636601 | 0.64 | — | — | |
| SCHEMBL23922214 | 0.64 | TOP2A (0.37) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL17716288 | 0.64 | TOP2A (0.46) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL23580046 | 0.63 | NR1H2 (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL15740850 | 0.63 | ALDH1A1 (0.33) | CRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11148998-B2 | Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11148998-B2 | Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof | RARB, RXRB, RXRA | CRHBP 2151/4885CRHR2 2506/4885ALDH1A1 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.