Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.60 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.53 |
| ▸ | NT5E | P21589 | 2/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.53 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.53 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.53 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.52 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.52 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.50 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23922254 | 0.93 | P2RX3 (0.58) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL22393015 | 0.88 | P2RX3 (0.53) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL23922227 | 0.87 | ENPP1 (0.71) | P2RX3P2RX4P2RX2P2RX1ENPP1 | |
| SCHEMBL22402627 | 0.87 | ENPP1 (0.71) | P2RX3P2RX4P2RX2P2RX1ENPP1 | |
| SCHEMBL26937426 | 0.87 | P2RX3 (0.51) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL26361369 | 0.87 | P2RX3 (0.51) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL22393010 | 0.83 | P2RX3 (0.47) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL22393012 | 0.83 | P2RX3 (0.47) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL26361444 | 0.82 | P2RX3 (0.47) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL22393104 | 0.81 | ENPP1 (0.72) | P2RX3P2RX4P2RX2P2RX1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840551-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2023-12-12 | — | — | US | disclosed |
| US-20220017560-A1 | COMPOSITIONS AND METHODS OF MODULATING THE IMMUNE RESPONSE BY ACTIVATING ALPHA PROTEIN KINASE 1 | WUXI PHARMATECH HEALTHCARE FUND I L.P. (CN) | 2022-01-20 | — | — | US | disclosed |
| US-11149051-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2021-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017560-A1 | COMPOSITIONS AND METHODS OF MODULATING THE IMMUNE RESPONSE BY ACTIVATING ALPHA PROTEIN KINASE 1 | PHKA1, PHKA2, PRKCA | P2RX3 1233/4885P2RX4 2015/4885P2RX2 1042/4885 |
| US-11149051-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | PHKA1, PHKA2, PRKCA | P2RX3 1233/4885P2RX4 2015/4885P2RX2 1042/4885 |
| US-11840551-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | PHKA1, PHKA2, PRKCA | P2RX3 1233/4885P2RX4 2015/4885P2RX2 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.