SCHEMBL23922317

SCHEMBL23922317

Cc1ccc2c3ccccc3n(-c3ncnc(I)n3)c2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.34
AURKA O14965 1/20 0.34
LMNA P02545 3/20 0.33
HTT P42858 2/20 0.33
MAPT P10636 2/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22926682 0.90 AURKA (0.37) AURKALMNAHTTMAPTPIK3CD
SCHEMBL20313304 0.86 MTOR (0.44) AURKALMNAHTTMAPTPIK3CD
SCHEMBL20322322 0.86 KDM4E (0.33) EGFRKDM4EATML3MBTL1
SCHEMBL23922333 0.85 PDE10A (0.36) ALDH1A1PDE10AATM
SCHEMBL22926685 0.81 MEN1 (0.40) AURKALMNAHTTMAPTPIK3CD
SCHEMBL23922340 0.81 SMN1; SMN2 (0.35) AURKALMNAHTTMAPTGABRP
SCHEMBL22926684 0.81 LMNA (0.41) AURKALMNAHTTMAPTGABRP
SCHEMBL14407561 0.81 LMNA (0.41) AURKALMNAHTTMAPTGABRP
SCHEMBL20313311 0.78 KDM4E (0.43) AURKALMNAHTTMAPTGABRP
SCHEMBL25640703 0.77 LMNA (0.38) AURKALMNAHTTMAPTPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210399242-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-23 US disclosed
US-11152579-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210399242-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 TNF 4714/4885AURKA 3524/4885LMNA 696/4885
US-11152579-B2 Organic electroluminescent materials and devices CACNA2D2, RABGGTA, NUDT1 TNF 4568/4885AURKA 1276/4885LMNA 2584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.