SCHEMBL23922342

SCHEMBL23922342

Cc1cncc(-c2cccc(I)n2)c1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 5/20 0.43
CYP11B1 P15538 4/20 0.43
CYP2A6 P11509 4/20 0.41
KARS1 Q15046 1/20 0.40
PIM1 P11309 2/20 0.37
PIM3 Q86V86 2/20 0.37
PIM2 Q9P1W9 2/20 0.37
S1PR1 P21453 2/20 0.36
TDO2 P48775 1/20 0.36
KMO O15229 1/20 0.35
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
ABL1 P00519 1/20 0.34
BCR P11274 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3423404 0.87 CYP11B1 (0.49) CYP11B2CYP11B1CYP2A6KARS1PIM1
SCHEMBL20322341 0.82 CYP2A6 (0.36) CYP2A6KARS1
SCHEMBL10001003 0.82 CYP2A6 (0.61) CYP11B2CYP11B1CYP2A6KARS1PIM1
SCHEMBL18019287 0.80 KMO (0.47) KARS1KMOKDM4E
SCHEMBL28090003 0.79 CYP11B2 (0.43) CYP11B2CYP11B1CYP2A6KARS1PIM1
SCHEMBL3422003 0.79 CYP2A6 (0.57) CYP11B2CYP11B1CYP2A6KARS1PIM1
SCHEMBL16848104 0.74 CYP2A6 (0.42) CYP11B2CYP11B1CYP2A6S1PR1TDO2
SCHEMBL15750395 0.73 CYP2A6 (0.62) CYP2A6KARS1KDM4ECYP3A4ABL1
SCHEMBL3421988 0.72 CYP2A6 (0.67) CYP2A6
SCHEMBL5144659 0.71 CYP2A6 (0.56) CYP11B2CYP11B1CYP2A6KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11152579-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11152579-B2 Organic electroluminescent materials and devices CACNA2D2, RABGGTA, NUDT1 CYP11B2 2585/4885CYP11B1 3425/4885CYP2A6 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.