Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 3/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 7/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21196687 | 0.84 | SLC6A5 (0.34) | P2RY14SLC6A5KCNH2CACNA1IHTR1A | |
| SCHEMBL19745998 | 0.81 | SLC6A5 (0.37) | SLC6A5CCR2MAPK1 | |
| SCHEMBL21214282 | 0.80 | TRPV1 (0.35) | SLC6A5MAPK1 | |
| Hydrochloric Acid SCHEMBL23922745 | 0.79 | TRPV1 (0.34) | SLC6A5MAPK1 | |
| SCHEMBL21214284 | 0.79 | SLC6A5 (0.38) | SLC6A5KCNH2CACNA1IDRD2DRD3 | |
| SCHEMBL21214241 | 0.79 | RHOC (0.40) | SLC6A5CCR2 | |
| Hydrochloric Acid SCHEMBL21196641 | 0.78 | RHOC (0.40) | SLC6A5CCR2 | |
| Trifluoroacetic Acid SCHEMBL23922747 | 0.78 | CCR2 (0.37) | SLC6A5DRD2DRD3CHRM2CHRM4 | |
| Trifluoroacetic Acid SCHEMBL21196768 | 0.78 | CHRM2 (0.39) | SLC6A5CHRM2CHRM4CHRM1MAPK1 | |
| Trifluoroacetic Acid SCHEMBL21196623 | 0.78 | CHRM2 (0.39) | SLC6A5CHRM2CHRM4CHRM1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-B1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-10-20 | — | — | EP | disclosed |