Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924073 | 1.00 | GRIN1 (0.44) | GRIN1GRIN2BHCRTR1HCRTR2KCNA3 | |
| SCHEMBL23924097 | 1.00 | GRIN1 (0.44) | GRIN1GRIN2BHCRTR1HCRTR2KCNA3 | |
| SCHEMBL28932927 | 0.87 | RORC (0.46) | GRIN1GRIN2BHCRTR1HCRTR2P2RX7 | |
| SCHEMBL23924114 | 0.82 | KCNA3 (0.46) | GRIN1GRIN2BHCRTR1HCRTR2KCNA3 | |
| SCHEMBL23924496 | 0.81 | TRPV1 (0.45) | KDM4ETRPV1NSD2ALDH1A1LMNA | |
| SCHEMBL23924495 | 0.81 | TRPV1 (0.45) | KDM4ETRPV1NSD2ALDH1A1LMNA | |
| SCHEMBL23924256 | 0.79 | KMT2A (0.48) | NPC1NR2F2KDM4ETRPV1NSD2 | |
| SCHEMBL23924009 | 0.79 | KMT2A (0.48) | NPC1NR2F2KDM4ETRPV1NSD2 | |
| SCHEMBL23924265 | 0.77 | ALDH1A1 (0.41) | HCRTR1HCRTR2CHRM1P2RX7ROCK2 | |
| SCHEMBL23951474 | 0.76 | KCNA3 (0.44) | GRIN1GRIN2BHCRTR1HCRTR2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S.R.L. (IT) | 2022-07-07 | — | — | US | disclosed |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S R L (IT) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | GRIN1 81/4885GRIN2B 80/4885HCRTR1 1936/4885 |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | GRIN1 81/4885GRIN2B 80/4885HCRTR1 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.