Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.44 |
| ▸ | PRKCG | P05129 | 3/20 | 0.44 |
| ▸ | PRKCB | P05771 | 3/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.44 |
| ▸ | PRKCH | P24723 | 3/20 | 0.44 |
| ▸ | PRKCI | P41743 | 3/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PRKACA | P17612 | 2/20 | 0.44 |
| ▸ | PRKACG | P22612 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924195 | 1.00 | P2RX7 (0.48) | P2RX7CHRM1PRKD3PRKCGPRKCB | |
| SCHEMBL23951468 | 0.88 | P2RX7 (0.49) | P2RX7CHRM1PRKD3PRKCGPRKCB | |
| SCHEMBL23923979 | 0.80 | PRKD3 (0.46) | P2RX7PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL30114565 | 0.80 | PRKD3 (0.46) | P2RX7PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL23951469 | 0.80 | PRKD3 (0.46) | P2RX7PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL23924376 | 0.77 | KMT2A (0.53) | MEN1KMT2ALMNASMN1; SMN2MAPK1 | |
| SCHEMBL23924378 | 0.77 | KMT2A (0.53) | MEN1KMT2ALMNASMN1; SMN2MAPK1 | |
| SCHEMBL23924073 | 0.76 | GRIN1 (0.44) | P2RX7CHRM1LMNASMN1; SMN2NSD2 | |
| SCHEMBL23924075 | 0.76 | GRIN1 (0.44) | P2RX7CHRM1LMNASMN1; SMN2NSD2 | |
| SCHEMBL23924097 | 0.76 | GRIN1 (0.44) | P2RX7CHRM1LMNASMN1; SMN2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S.R.L. (IT) | 2022-07-07 | — | — | US | disclosed |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S R L (IT) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | P2RX7 3078/4885CHRM1 3119/4885PRKD3 1591/4885 |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | P2RX7 3078/4885CHRM1 3119/4885PRKD3 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.