Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | F13A1 | P00488 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA6 | P23280 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 2/20 | 0.56 |
| ▸ | THPO | P40225 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.56 |
| ▸ | CASP2 | P42575 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Spermidine SCHEMBL28486989 | 0.98 | CA12 (0.58) | CA12F13A1CA2CYP1A2ALOX15 | |
| Acrylic Acid SCHEMBL29838100 | 0.89 | CA12 (0.50) | CA12F13A1CA2CYP1A2ALOX15 | |
| Spermine SCHEMBL25404718 | 0.87 | CA12 (0.56) | CA12F13A1CA2CYP1A2ALOX15 | |
| Acrylic Acid SCHEMBL31412763 | 0.87 | MAOA (0.47) | CA12F13A1CA2CYP1A2ALOX15 | |
| Acrylic Acid SCHEMBL9250272 | 0.86 | CA12 (0.52) | CA12F13A1CA2CYP1A2ALOX15 | |
| Acrylic Acid SCHEMBL1399453 | 0.86 | PAOX (0.43) | CA12F13A1CA2CYP1A2ALOX15 | |
| Spermine SCHEMBL3060219 | 0.84 | CA12 (0.59) | CA12F13A1CA2CYP1A2ALOX15 | |
| Norspermidine SCHEMBL9615504 | 0.84 | CA12 (0.52) | CA12F13A1CA2CYP1A2ALOX15 | |
| Spermine SCHEMBL3060222 | 0.84 | CA12 (0.59) | CA12F13A1CA2CYP1A2ALOX15 | |
| Spermidine SCHEMBL3059084 | 0.83 | CA12 (0.61) | CA12F13A1CA2CYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220323605-A1 | Gene Editing Nanocapsule and Preparation Method and Use Thereof | HENAN UNIVERSITY (CN) | 2022-10-13 | — | — | US | claimed |
| US-20210322330-A1 | siRNA Nanocapsule and Preparation Method and Use thereof | HENAN UNIVERSITY (CN) | 2021-10-21 | — | — | US | claimed |
| CN-112972703-A | Gene editing nanocapsule and preparation method and application thereof | 河南大学 | 2021-06-18 | — | — | CN | claimed |
| CN-111481679-A | siRNA nanocapsule and preparation method and application thereof | 河南大学 | 2020-08-04 | — | — | CN | claimed |
| US-12076416-B2 | Gene editing nanocapsule and preparation method and use thereof | HENAN UNIVERSITY (CN) | 2024-09-03 | — | — | US | disclosed |
| US-11793764-B2 | siRNA nanocapsule and preparation method and use thereof | HENAN UNIVERSITY (CN) | 2023-10-24 | — | — | US | disclosed |
| CN-112972703-B | Gene editing nano capsule and its preparation method and application | 河南大学 | 2023-04-28 | — | — | CN | disclosed |
| US-20220323605-A1 | Gene Editing Nanocapsule and Preparation Method and Use Thereof | HENAN UNIVERSITY (CN) | 2022-10-13 | — | — | US | disclosed |
| CN-111481679-B | siRNA nanocapsule and preparation method and application thereof | 河南大学 | 2022-02-01 | — | — | CN | disclosed |
| US-20210322330-A1 | siRNA Nanocapsule and Preparation Method and Use thereof | HENAN UNIVERSITY (CN) | 2021-10-21 | — | — | US | disclosed |
| CN-112972703-A | Gene editing nanocapsule and preparation method and application thereof | 河南大学 | 2021-06-18 | — | — | CN | disclosed |
| CN-111481679-A | siRNA nanocapsule and preparation method and application thereof | 河南大学 | 2020-08-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11793764-B2 | siRNA nanocapsule and preparation method and use thereof | HNRNPAB, ACTB, SNRPE | CA12 2381/4885F13A1 1723/4885CA2 3384/4885 |
| US-12076416-B2 | Gene editing nanocapsule and preparation method and use thereof | RNASE1, LDLR, CASK | CA12 1926/4885F13A1 3556/4885CA2 2914/4885 |
| US-20220323605-A1 | Gene Editing Nanocapsule and Preparation Method and Use Thereof | RNASE1, LDLR, CASK | CA12 1926/4885F13A1 3556/4885CA2 2914/4885 |
| US-20210322330-A1 | siRNA Nanocapsule and Preparation Method and Use thereof | HNRNPAB, ACTB, SNRPE | CA12 2381/4885F13A1 1723/4885CA2 3384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.