SCHEMBL23924832

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25203235	1.00	LMNA (0.36)	LMNACYP2D6PRMT5WDR77ALDH1A1
	SCHEMBL25640465	0.89	CYP2D6 (0.48)	LMNACYP2D6ALDH1A1FAAHTSHR
	SCHEMBL25640538	0.85	LMNA (0.51)	LMNAALDH1A1TSHRNPSR1
	SCHEMBL25743441	0.85	LMNA (0.51)	LMNAALDH1A1TSHRNPSR1
	SCHEMBL30287271	0.84	LMNA (0.43)	LMNACYP2D6ALDH1A1KCNJ1TSHR
	SCHEMBL25190457	0.83	LMNA (0.37)	LMNACYP2D6PRMT5WDR77KCNJ1
	SCHEMBL23924923	0.83	LMNA (0.37)	LMNACYP2D6PRMT5WDR77KCNJ1
	SCHEMBL30034375	0.81	KMT2A (0.46)	LMNAALDH1A1
	SCHEMBL25192315	0.81	KMT2A (0.46)	LMNAALDH1A1
	SCHEMBL23943614	0.81	KMT2A (0.46)	LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.