Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25743441 | 0.94 | LMNA (0.51) | LMNATSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL25640538 | 0.94 | LMNA (0.51) | LMNATSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL30287271 | 0.93 | LMNA (0.43) | CYP2D6LMNATSHRKDM4EHSD17B10 | |
| SCHEMBL23924832 | 0.89 | LMNA (0.36) | CYP2D6LMNATSHRFAAHALDH1A1 | |
| SCHEMBL25203235 | 0.89 | LMNA (0.36) | CYP2D6LMNATSHRFAAHALDH1A1 | |
| SCHEMBL25353494 | 0.85 | CYP2D6 (0.46) | CYP2D6LMNATSHRSMN1; SMN2KMT2A | |
| SCHEMBL25353488 | 0.85 | CYP2D6 (0.46) | CYP2D6LMNATSHRSMN1; SMN2KMT2A | |
| SCHEMBL30453323 | 0.85 | CYP2D6 (0.46) | CYP2D6LMNATSHRSMN1; SMN2KMT2A | |
| SCHEMBL25743783 | 0.85 | LMNA (0.36) | CYP2D6LMNAFAAHCHRM3PDE2A | |
| SCHEMBL23943578 | 0.84 | LMNA (0.37) | CYP2D6LMNATSHRFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |