SCHEMBL23924840

SCHEMBL23924840

FC(F)(F)c1ccc(N2CCOCC2)c(Nc2cnc3ccccc3n2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
KDM4E B2RXH2 5/20 0.57
TSHR P16473 4/20 0.57
HPGD P15428 3/20 0.57
LMNA P02545 3/20 0.57
MAPT P10636 3/20 0.57
HSD17B10 Q99714 3/20 0.57
TP53 P04637 2/20 0.57
MAPK1 P28482 2/20 0.57
MEN1 O00255 1/20 0.57
USP2 O75604 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
KMT2A Q03164 1/20 0.57
GPR55 Q9Y2T6 1/20 0.57
GAA P10253 3/20 0.52
NPSR1 Q6W5P4 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23925095 0.90 MAPT (0.47) ALDH1A1KDM4ETSHRHPGDLMNA
SCHEMBL23925024 0.89 KDR (0.47) ALDH1A1KDM4ETSHRHPGDLMNA
SCHEMBL23925270 0.87 MET (0.51) ALDH1A1KDM4ETSHRHPGDLMNA
SCHEMBL23925278 0.83 ALDH1A1 (0.51) ALDH1A1KDM4ETSHRHPGDLMNA
SCHEMBL23924951 0.81 ALDH1A1 (0.65) ALDH1A1KDM4ETSHRHPGDLMNA
SCHEMBL13006748 0.72 ALDH1A1 (0.70) ALDH1A1KDM4ETSHRLMNAHSD17B10
SCHEMBL22169111 0.72 ALDH1A1 (0.64) ALDH1A1KDM4ETSHRLMNAMAPT
SCHEMBL30360594 0.70 KDM4E (0.69) ALDH1A1KDM4ETSHRHPGDHSD17B10
SCHEMBL30360593 0.70 KDM4E (0.69) ALDH1A1KDM4ETSHRHPGDHSD17B10
SCHEMBL28292119 0.70 KDM4E (0.69) ALDH1A1KDM4ETSHRHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021209490-A1 CYCLAMINEPHENYLAMINOQUINOLINES AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-10-21 WO claimed
WO-2021209490-A1 CYCLAMINEPHENYLAMINOQUINOLINES AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-10-21 WO disclosed