SCHEMBL23925278

SCHEMBL23925278

c1ccc(N2CCOCC2)c(Nc2cnc3ccccc3n2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
KDM4E B2RXH2 2/20 0.51
MAPT P10636 2/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 1/20 0.51
KMT2A Q03164 1/20 0.51
NPSR1 Q6W5P4 3/20 0.48
TSHR P16473 2/20 0.48
RHOA P61586 1/20 0.48
POLB P06746 3/20 0.48
PDGFRB P09619 1/20 0.47
PDGFRA P16234 1/20 0.47
P2RX7 Q99572 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
EPHB4 P54760 1/20 0.45
TGFBR1 P36897 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23924840 0.83 ALDH1A1 (0.57) ALDH1A1HPGDKDM4EMAPTMAPK1
SCHEMBL31620790 0.83 NPSR1 (0.61) ALDH1A1HPGDKDM4EMAPTMAPK1
SCHEMBL6236440 0.80 SLC2A1 (0.54) ALDH1A1HPGDKDM4EMAPTMAPK1
SCHEMBL581984 0.78 HPGD (0.53) ALDH1A1HPGDKDM4EMAPTMAPK1
SCHEMBL6087670 0.78 NCF1 (0.53) ALDH1A1HPGDKDM4EMAPTMAPK1
SCHEMBL6105362 0.78 NCF1 (0.56) ALDH1A1HPGDKDM4EMAPTMAPK1
SCHEMBL6100736 0.75 EPHB4 (0.57) ALDH1A1HPGDKDM4EMAPTMAPK1
SCHEMBL18335243 0.75 ALDH1A1 (0.53) ALDH1A1HPGDKDM4EMAPTMAPK1
SCHEMBL4346005 0.74 PIK3CA (0.52) ALDH1A1MAPK1LMNA
SCHEMBL4350228 0.74 PIK3CA (0.67) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021209490-A1 CYCLAMINEPHENYLAMINOQUINOLINES AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-10-21 WO claimed
WO-2021209490-A1 CYCLAMINEPHENYLAMINOQUINOLINES AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-10-21 WO disclosed