Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412000 | 0.85 | DPP4 (0.51) | TSHRLMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL7497591 | 0.85 | DPP4 (0.51) | TSHRLMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL1584098 | 0.81 | TSHR (0.48) | TSHRLMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL4388067 | 0.79 | KMT2A (0.52) | LMNAKDM4EKMT2AALDH1A1MAPK1 | |
| SCHEMBL22440090 | 0.78 | TSHR (0.46) | TSHRLMNAL3MBTL1KDM4EKMT2A | |
| Dimethylamine SCHEMBL28896303 | 0.76 | TSHR (0.49) | TSHRLMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL2299168 | 0.75 | DPP4 (0.53) | TSHRLMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL29171350 | 0.75 | DPP4 (0.53) | TSHRLMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL9003054 | 0.74 | KMT2A (0.68) | TSHRLMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL9003051 | 0.74 | KMT2A (0.68) | TSHRLMNAL3MBTL1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4136084-A1 | BCL-2 INHIBITOR | BeiGene, Ltd. (KY) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |