Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22440090 | 0.94 | TSHR (0.46) | TSHRL3MBTL1KMT2AFAAHNAAA | |
| SCHEMBL9029302 | 0.81 | L3MBTL1 (0.41) | TSHRL3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL9029295 | 0.81 | L3MBTL1 (0.41) | TSHRL3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL23925182 | 0.81 | TSHR (0.50) | TSHRL3MBTL1KMT2AALDH1A1KDM4E | |
| Dimethylamine SCHEMBL28896303 | 0.80 | TSHR (0.49) | TSHRL3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL7497591 | 0.77 | DPP4 (0.51) | TSHRL3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL7412000 | 0.77 | DPP4 (0.51) | TSHRL3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL9003051 | 0.75 | KMT2A (0.68) | TSHRL3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL9003054 | 0.75 | KMT2A (0.68) | TSHRL3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL28433612 | 0.74 | KMT2A (0.51) | TSHRKMT2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |