Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412000 | 1.00 | DPP4 (0.51) | DPP4TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL23925182 | 0.85 | TSHR (0.50) | TSHRL3MBTL1KDM4ELMNAKMT2A | |
| SCHEMBL2299168 | 0.84 | DPP4 (0.53) | DPP4TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL29171350 | 0.84 | DPP4 (0.53) | DPP4TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL14518853 | 0.81 | DPP4 (0.47) | DPP4TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL4064197 | 0.78 | KMT2A (0.53) | DPP4KDM4ELMNAKMT2AALDH1A1 | |
| SCHEMBL4064196 | 0.78 | KMT2A (0.53) | DPP4KDM4ELMNAKMT2AALDH1A1 | |
| Dimethylamine SCHEMBL28896303 | 0.78 | TSHR (0.49) | TSHRL3MBTL1KDM4ELMNAKMT2A | |
| SCHEMBL1584098 | 0.77 | TSHR (0.48) | TSHRL3MBTL1KDM4ELMNAKMT2A | |
| SCHEMBL9003054 | 0.77 | KMT2A (0.68) | TSHRL3MBTL1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |